Methods for increasing isoprenoid and isoprenoid precursor production by modulating fatty acid levels
US8114645B2 · kind B2 · utility
5Cited by
7References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 17, 2007 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Feb 27, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P23/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods of increasing production of an isoprenoid or an isoprenoid precursor in a host cell, the methods generally involving modulating the level of activity of a fatty acid biosynthetic pathway enzyme in the host cell and/or culturing the host cell in a culture medium comprising a fatty acid or a compound that can be metabolized in a cell or broken down in the medium to yield a fatty acid and/or culturing the host cell in a culture medium having increased osmolarity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.