Linear and cyclic melanocortin receptor-specific peptidomimetics
US8114844B2 · kind B2 · utility
13Cited by
9References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 3, 2008 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Oct 15, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Linear and cyclic peptidomimetics which bind to one or more melanocortin receptors are provided, which peptidomimetics include at least one ring-constrained amino acid surrogate of formula I:where R1, R2, R3, R4, R5, R6, R7, R8, and y are as defined in the specification, together with methods for synthesizing ring-constrained amino acid surrogates of formula I and peptidomimetics incorporating the same, and methods of use of peptidomimetics in the treatment of various diseases, syndromes and conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.