Patent · US Active

GABA-steroid antagonists and their use for the treatment of CNS disorders

US8114860B2 · kind B2 · utility

4Cited by

1References

3Claims

0Family size

Assignee

UMECRINE AB · SE

Inventors

Torbjörn Bäckström · Umeå, SE
Per Lundgren · Väröbacka, SE
Ming Wang · Montgomery, US

Key dates

Filing date	Nov 7, 2005
Grant date	Feb 14, 2012
Priority date	—
Expiry date	Oct 17, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds exhibiting 3alpha-hydroxy-5alpha/beta-steroid blocking action with no or only low antagonism against the gamma-aminobutyric acid (A) receptor (GABA-A), and compounds exhibiting partial antagonism against said receptor are presented. Methods for the prevention, treatment and/or alleviation of various CNS-disorders are suggested, as well as pharmaceutical compositions for such use.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.