Patent · US Active

Macrolide antibiotics and their use for medical purposes

US8114864B2 · kind B2 · utility

0Cited by

0References

14Claims

0Family size

Assignee

Helmholtz-Zentrum Für Infektionsforschung GmbH · DE

Inventors

Rolf Jansen · Braunschweig, DE
Brigitte Kunze · Braunschweig, DE
Herbert Irschik · Wittmund, DE

Key dates

Filing date	Nov 9, 2007
Grant date	Feb 14, 2012
Priority date	—
Expiry date	May 20, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D513/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides novel Thuggacin-Type macrolide compounds which form rearrangement products forming a lacton bond to different carbon atoms. The novel compounds can be produced by fermentation of Sorangium cellulosum and Chondromyces crocatus and can be isolated by adsorption and chromoatograhic processing steps. The compounds are found to have antibiotic activity. The invention also relates to Thuggacin A, Thuggacin B, Thuggacin C, 13-Methyl-Thuggacin A, Thuggacin CMC-A, Thuggacin CMC-B and Thuggacin CMC-C AS Antimycobacterial Agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.