1,4-disubstituted naphthalenes as inhibitors of p38 map kinase
US8114873B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Aug 11, 2010 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Aug 11, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Naphthalene-based compounds having linked heterocyclic and aromatic rings capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating conditions associated with P38 activity or cytokine activity; more particularly naphthalene-based compounds of Formula (I) having a morpholine heterocyclic ring, and methods of use thereof
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.