Compositions of PSMA antibodies
US8114965B2 · kind B2 · utility
37Cited by
75References
47Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Nov 7, 2007 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Nov 7, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention includes antibodies or antigen-binding fragments thereof which bind specifically to conformational epitopes on the extracellular domain of PSMA, compositions containing one or a combination of such antibodies or antigen-binding fragments thereof, hybridoma cell lines that produce the antibodies, and methods of using the antibodies or antigen-binding fragments thereof for cancer diagnosis and treatment. The invention also includes oligomeric forms of PSMA proteins, compositions comprising the multimers, and antibodies that selectively bind to the multimers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.