Peptide-based passive immunization therapy for treatment of atherosclerosis
US8114966B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 27, 2008 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Apr 22, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to passive immunization for treating or preventing atherosclerosis using an isolated human antibody directed towards at least one oxidized fragment of apolipoprotein B in the manufacture of a pharmaceutical composition for therapeutical or prophylactical treatment of atherosclerosis by means of passive immunization, as well as method for preparing such antibodies, and a method for treating a mammal, preferably a human using such an antibody to provide for passive immunization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.