Polymer conjugates of mutated neublastin
US8119114B2 · kind B2 · utility
2Cited by
52References
60Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 27, 2008 |
| Grant date | Feb 21, 2012 |
| Priority date | — |
| Expiry date | Aug 29, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A dimer comprising a mutated neublastin polypeptide coupled to a polymer is disclosed. Such dimers exhibit prolonged bioavailability and, in preferred embodiments, prolonged biological activity relative to wild-type forms of neublastin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.