Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
US8119125B2 · kind B2 · utility
13Cited by
3References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 11, 2006 |
| Grant date | Feb 21, 2012 |
| Priority date | — |
| Expiry date | Dec 1, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21026
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for stabilizing polypeptides for oral administration, particularly where enteric delivery is desirable. By administering the polypeptides with a bile sequestering agent, the stability of the polypeptide can be increased. Pharmaceutical formulations for this purpose are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.