Patent · US Active

Antibodies that bind urokinase-type plasminogen activator and epitopes therefor

US8119128B2 · kind B2 · utility

1Cited by

5References

10Claims

0Family size

Assignee

The Regents of the University of Colorado, a Body Corporate · US

Inventor

Edward Abraham · Hanover, US

Key dates

Filing date	Oct 28, 2005
Grant date	Feb 21, 2012
Priority date	—
Expiry date	Jul 8, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K16/40
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Anti-uPA antibodies and antigen-binding regions thereof, as well as pharmaceutical compositions comprising such antibodies and antigen-binding regions, are described. Also described are methods of using such antibodies and antigen-binding regions to bind uPA epitopes and activate uPA function, such as inhibition of uPA mediated inflammation. Epitopes that can be used to activate uPA function and anti-inflammation activity are also described, as well as methods of identifying compounds that can bind them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.