Disease model incorporation into an artificial immune system (AIS)
US8119403B2 · kind B2 · utility
2Cited by
12References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 5, 2010 |
| Grant date | Feb 21, 2012 |
| Priority date | — |
| Expiry date | Mar 5, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising a three-dimensional matrix comprising lymphoid tissue, a three-dimensional matrix comprising epithelial and/or endothelial cells, and diseased cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.