Cell marker for hepatic and pancreatic stem cells and progenitor cells
US8119774B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Oct 8, 2004 |
| Grant date | Feb 21, 2012 |
| Priority date | — |
| Expiry date | Aug 29, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2503/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a cell marker that is characterized by binding to a GCTM-5 antibody of active fragment. The cell marker identifies a unique sub-population of stem cells that show characteristics of hepatic or pancreatic stem cells or hepatic or pancreatic progenitor cells. More specifically the marker is an early liver marker, which could prove a useful tool for the isolation and identification of liver and pancreatic progenitors for both diseased adult liver and differentiating human embryonic stem cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.