AMPK-activating heterocycloalkyloxy(hetero)aryl carboxamide, sulfonamide and amine compounds and methods for using the same
US8119809B2 · kind B2 · utility
13Cited by
7References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 17, 2008 |
| Grant date | Feb 21, 2012 |
| Priority date | — |
| Expiry date | Mar 10, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structurein which R1, R2, R4, E, T, n and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.