Method and apparatus for generation of reagent ions in a mass spectrometer
US8119984B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 28, 2009 |
| Grant date | Feb 21, 2012 |
| Priority date | — |
| Expiry date | Nov 14, 2029 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/12
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
A front-end reagent ion source for a mass spectrometer is disclosed. Reagent vapor is supplied to a reagent ionization volume located within a chamber of the mass spectrometer and maintained at a low vacuum pressure. Reagent ions are formed by interaction of the reagent vapor molecules with an electrical discharge (e.g., a glow discharge) within the ionization volume, and pass into the chamber of the mass spectrometer. At least one ion optical element located along the analyte ion path transports the reagent ions to successive chambers of the mass spectrometer. The reagent ions may be combined with the analyte ions to perform ion-ion studies such as electron transfer dissociation (ETD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.