Freeze indicators with a controlled temperature response
US8122844B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 30, 2010 |
| Grant date | Feb 28, 2012 |
| Priority date | — |
| Expiry date | Sep 23, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01K11/18
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A freeze indicator can include an indicator dispersion having an aqueous liquid medium and organic material indicator particles dispersed in the aqueous liquid medium. The indicator dispersion can have an initial appearance before freezing and an irreversibly different appearance after freezing and can exhibit a freeze-onset temperature of about −1.9° C. or higher. Some factors helpful to providing a relatively high freeze onset temperature are employment of a proteinaceous ice-nucleating agent, control of pH, use of a protein stabilizer and control of the ratio of protein stabilizer to ice-nucleating agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.