Patent · US Active

Human monoclonal antibody having fat-reducing effect

US8124080B2 · kind B2 · utility

1Cited by
10References
27Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 12, 2004
Grant dateFeb 28, 2012
Priority date
Expiry dateApr 14, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/565
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A purified polypeptide having an amino acid sequence that is substantial identical with the amino acid sequence of SEQ ID NO:1, SEQ ID NO:3, or both, in which the polypeptide binds low density lipoproteins (LDL) or oxidized LDL (oxLDL), or both, and particularly binds well to LDL cholesterol and oxidized LDL cholesterol. The polypeptide may be used in combination with conventional adjuvants or carrier substances for producing a drug having a fat-reducing effect and for producing drugs for aiding in the treatment of renal diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.