Compositions and methods for destabilizing lysosomes to increase oncogenic or aberrant protein degradation
US8124371B2 · kind B2 · utility
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2References
1Claims
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Key dates
| Filing date | Jul 30, 2004 |
| Grant date | Feb 28, 2012 |
| Priority date | — |
| Expiry date | Aug 31, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2814
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions for destabilizing lysosomes to increase the degradation of oncogenic or aberrant proteins for the prevention or treatment of disease. Methods for identifying agents which destabilize lysosomes are also provided as are agents identified in accordance with the screening method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.