Process and materials for production of glucosamine and N-acetylglucosamine

US8124381B2 · kind B2 · utility

Assignee

• Arkion Life Sciences, LLC · US

Inventors

• Ming-De Deng · Manitowoc, US
• J. David Angerer
• Don Cyron · McKeesport, US
• Alan D. Grund · Manitowoc, US
• Thomas A. Jerrell · Manitowoc, US
• Candice Leanna · Green Bay, US
• Owen Mathre · Wilmington, US
• Reinhardt Rosson · Manitowoc, US
• Jeff Running · Manitowoc, US
• Dave Severson · Two Rivers, US
• Linsheng Song · Manitowoc, US
• Sarah Wassink · Sheboygan, US

Key dates

• Filing date: Dec 19, 2007
• Grant date: Feb 28, 2012
• Expiry date: Dec 25, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/52
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A biosynthetic method for producing glucosamine and N-acetylglucosamine is disclosed. Such a method includes the fermentation of a genetically modified microorganism to produce glucosamine and/or N-acetylglucosamine. Also disclosed are genetically modified microorganisms that are useful for producing glucosamine and N-acetylglucosamine. In addition, methods of recovering N-acetylglucosamine that has been produced by a fermentation process, including methods that result in N-acetylglucosamine of high purity, are described. Also disclosed is a method to produce glucosamine from N-acetylglucosamine.