Stable integrands
US8124404B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 1, 2004 |
| Grant date | Feb 28, 2012 |
| Priority date | — |
| Expiry date | Apr 8, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
There is provided a transposable element comprising at least four inverted repeats, at least two of which are each inverted in relation to another, the element comprising DNA for insertion into a host genome, the DNA being located between two pairs of opposing repeats excisable by a transposase in situ to leave said DNA without flanking transposon-derived repeats in the host genome. Also provided is a transposable element comprising at least three inverted repeats, at least one of which is inverted in relation to the others, wherein at least one non-terminal repeat is a minimal repeat. Both these elements allow for greater efficiency of insertion of nucleotide sequences into the genome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.