Spirotropane compounds
US8124613B2 · kind B2 · utility
2Cited by
2References
38Claims
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Key dates
| Filing date | Jun 14, 2007 |
| Grant date | Feb 28, 2012 |
| Priority date | — |
| Expiry date | Feb 19, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds according to formula (I):wherein R1, R2, R3, n and X are defined as defined herein, and the pharmaceutically acceptable salts, hydrates and solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity. Additionally, compounds according to Formula III:wherein Z, R′1, and R′2 are defined as defined herein, and the pharmaceutically acceptable salts, hydrates and solvates thereof, are useful as intermediates for production of compounds that modulate CCR5 chemokine receptor activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.