Diketo substituted pyrrolo[2,3-C]pyridines

US8124615B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Tao Wang · Farmington, US
• Yasutsugu Ueda · Clinton, US
• Lawrence G. Hamann · North Grafton, US
• Zhongxing Zhang · Wallingford, US
• Zhiwei Yin · Glastonbury, US
• Alicia Regueiro-Ren · Wallingford, US
• David J. Carini · Wilmington, US
• Jacob Swidorski · Wallingford, US
• Zheng Liu · Beacon Falls, US
• Barry Johnson · Castle Rock, US
• Nicolas A. Meanwell · East Hampton, US
• John F. Kadow · Wallingford, US

Key dates

• Filing date: May 5, 2011
• Grant date: Feb 28, 2012
• Expiry date: May 5, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, diketo fused azolopiperidine and azolopiperazine derivatives of Formula I:that possess unique antiviral activity are provided. These compounds are useful for the treatment of HIV and AIDS.