ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors

US8124630B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Bernd Riedl · Wuppertal, DE
• Jacques Dumas · Neuilly-Plaisance, FR
• Uday Khire · Hamden, US
• Timothy B. Lowinger · Carlisle, US
• William Scott · Guilford, US
• Roger Smith · Madison, US
• Jill Wood · Hampton, US
• Reina Natero · Hamden, US

Key dates

• Filing date: Nov 27, 2001
• Grant date: Feb 28, 2012
• Expiry date: Jul 13, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.