Macrolide derivatives
US8124744B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 1, 2007 |
| Grant date | Feb 28, 2012 |
| Priority date | — |
| Expiry date | Nov 9, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds represented by formula (I) and the formula (IV) have an inhibitory activity of MMP-9 production, therefore, are useful as a medicine agent with fewer side effects than conventional MMP enzyme activity inhibitors, as a prophylactic and therapeutic drug for oncogenic angiogenesis, chronic rheumatoid arthritis, vascular intimal thickening after a percutaneous coronary transluminal angioplasty, vascular atherosclerosis, hemorrhagic apoplexy, acute myocardial infarction, chronic heart failure, aneurysm, lung cancer metastasis, adult respiratory distress syndrome, asthma, interstitial pulmonary fibrosis, chronic rhinosinusitis, bronchitis or chronic obstructive pulmonary disease (COPD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.