Spirocyclic cyclohexane compounds with analgesic activity

US8124788B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Beatrix Merla · Aachen, DE
• Stefan Oberboersch · Aachen, DE
• Bernd Sundermann · Aachen, DE
• Werner Englberger · Stolberg, DE
• Hagen-Heinrich Hennies · Simmerath, DE
• Babette-Yvonne Koegel · Eschweiler, DE
• Stephan Schunk · Heidelberg, DE
• Heinz Graubaum · Berlin, DE

Key dates

• Filing date: Oct 27, 2008
• Grant date: Feb 28, 2012
• Expiry date: Jul 2, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Spirocyclic cyclohexane compounds corresponding to formula Ia process for manufacturing such compounds, pharmaceutical compositions that contain such compounds, and the use of such spirocyclic cyclohexane compounds for the production of pharmaceuticals, and particularly for the treatment of pain.