Methods for using a three-dimensional stromal tissue to promote angiogenesis
US8128924B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 8, 2009 |
| Grant date | Mar 6, 2012 |
| Priority date | — |
| Expiry date | Apr 8, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/20
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to a method for promoting blood vessel formation in tissues and organs. In particular, the method relates to implantation or attachment of an engineered three-dimensional stromal tissue to promote endothelialization and angiogenesis in the heart and related tissues. The three-dimensional stromal tissue of the present invention may be used in a variety of applications including, but not limited to, promoting repair of and regeneration of damaged cardiac muscle, promoting vascularization and healing during cardiac surgery, promoting blood vessel formation at anastomosis sites, and promoting vascularization and repair of damaged skeletal muscle, smooth muscle or connective tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.