Drug delivery system targeting to estrogen receptor over-expressed cells
US8128945B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Sep 20, 2010 |
| Grant date | Mar 6, 2012 |
| Priority date | — |
| Expiry date | Sep 20, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/774
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A vector for targeted delivery of drugs into estrogen receptors over-expressed cells is disclosed. The vector of the present invention is mainly about an active targeting delivery carrier which consists of a plurality of nanoparticles including: (i) a plurality of targeted moiety conjugated to the outer surface of the nanoparticles, the moiety being capable of binding with the estrogen receptor of a target cell, and (ii) bioactive agents encapsulated in the nanoparticles or forming complex with the nanoparticles. The targeted moiety of the present invention can also be conjugated to parent drugs for prodrug design.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.