Patent · US Active

Pin1 as a marker for abnormal cell growth

US8129131B2 · kind B2 · utility

11Cited by

3References

10Claims

0Family size

Assignee

Beth Israel Deaconess Medical Center, Inc. · US

Inventors

Kun Ping Lu · Newton, US
Xiao Zhen Zhou · Newton, US
Gerburg Wulf · Cambridge, US

Key dates

Filing date	Jul 18, 2008
Grant date	Mar 6, 2012
Priority date	—
Expiry date	Apr 21, 2029

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/52
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an abnormal cell growth, such as breast or prostate cancer. In another embodiment, the method includes evaluating the efficacy of a treatment of an abnormal cell growth, such as cancer, by monitoring the levels of Pin1. In another embodiment, the method includes evaluating the extent of metastasis of abnormal cell growth, such as cancer. The levels of Pin1 can be protein levels or nucleic acid levels.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.