Selective enzymatic esterification and solvolysis of epimeric vitamin D analog and separation of the epimers
US8129173B2 · kind B2 · utility
9Cited by
11References
24Claims
0Family size
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Key dates
| Filing date | Jan 9, 2003 |
| Grant date | Mar 6, 2012 |
| Priority date | — |
| Expiry date | Dec 29, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/004
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided is a method of selectively enzymatically esterifying or selectively enzymatically solvolyzing epimers of analogs of vitamin D having a stereogenic center at C-24 that has a free or esterified OH group. The metod can be used, for example, for separating mixed epimers of the vitamin D analog.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.