Inhibitors of protein phosphatase 1, GADD34 and protein phosphatase 1/GADD34 complex, preparation and uses thereof
US8129340B2 · kind B2 · utility
2Cited by
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10Claims
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Key dates
| Filing date | Sep 7, 2007 |
| Grant date | Mar 6, 2012 |
| Priority date | — |
| Expiry date | Apr 8, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/916
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of a protein phosphatase inhibitor selected from an inhibitor of the catalytic subunit of the protein phosphatase 1 (PP1), an inhibitor of GADD34 and an inhibitor of the PP1/GADD34 complex to prepare a pharmaceutical composition to prevent or treat a cancer in a mammal, wherein the pharmaceutical composition is intended for administration in combination with a product used in a treatment of a cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.