Substituted thieno[2,3-d]pyrimidines as AMPA modulators
US8129397B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Nov 12, 2008 |
| Grant date | Mar 6, 2012 |
| Priority date | — |
| Expiry date | May 18, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a heterocyclic derivative according to formula Iwherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and learning and memory disorders such as Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.