System and method for co-registering multi-channel images of a tissue micro array
US8131476B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 7, 2006 |
| Grant date | Mar 6, 2012 |
| Priority date | — |
| Expiry date | Jul 22, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30072
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system and methods for co-registering multi-channel images of a tissue micro array, comprising the steps of, providing a biological material on a substrate; applying one or more molecular probes, adapted to provide fluorescent molecular markers, to the biological material; obtaining a first digital image of the biological material and the fluorescent molecular markers; applying a morphological stain to the biological material; obtaining a second digital image of the biological material, computing information common to the first and second images; and co-registering the second image with the first image based on one or more registration metrics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.