Composition comprising an antisense sequence implicated in the regulation of angiogenesis
US8133877B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 8, 2009 |
| Grant date | Mar 13, 2012 |
| Priority date | — |
| Expiry date | Jun 8, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Therapeutic compositions used in the field of angiogenesis include nucleotide sequences of genes, the involvement of the genes in the angiogenesis mechanism having been demonstrated by the Applicant, and including the complementary sequences thereof, the antisense sequences of same, polypeptide sequences coded by the coding parts of the aforementioned genes and antibodies that are directed against the polypeptide sequences and also relate to genetically-modified cells that underexpress or overexpress the above-mentioned genes and to therapeutic compositions containing the cells, which are used to treat angiogenic disorders, and, moreover, relate to methods of diagnosing and/or prognosticating antigenic disorders and to novel methods of screening active compounds in the treatment of the disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.