Bicyclic pyrimidine derivatives as calcium channel blockers
US8133998B2 · kind B2 · utility
48Cited by
2References
42Claims
0Family size
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Key dates
| Filing date | May 9, 2008 |
| Grant date | Mar 13, 2012 |
| Priority date | — |
| Expiry date | Dec 2, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing thienopyrimidine or oxoquinazoline derivatives are disclosed of the general formula (1) or formula (2) where X is a linker and Y is an aromatic moiety or N(R5)(R6).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.