Test object for use with diffusion MRI and system and method of synthesizing complex diffusive geometries using novel gradient directions
US8134363B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2008 |
| Grant date | Mar 13, 2012 |
| Priority date | — |
| Expiry date | Jun 10, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/58
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A test object for use with diffusion MRI and a system and methods of synthesizing complex diffusive geometries. The test object, which includes anisotropic structures, can be used to monitor DTI measures by providing a baseline measurement. Using measurements of the phantom, data characteristic of more complicated diffusive behavior can be “synthesized”, or composed of actual measurements re-arranged into a desired spatial distribution function describing diffusion. Unlike a typical DTI scan, the ADC measurements of the present invention are treated in a “reconstruction” phase as if the gradients were applied in different directions. Given a set of reconstruction directions, a judicious choice of acquisition directions for each reconstruction direction allows for the synthesis of any distribution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.