Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
US8137904B2 · kind B2 · utility
28Cited by
75References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 5, 2003 |
| Grant date | Mar 20, 2012 |
| Priority date | — |
| Expiry date | Feb 16, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described is the use of a microorganism or cell containing a DNA sequence encoding a detectable protein or a protein capable of inducing a detectable signal, e.g., a luminescent or fluorescent protein for the preparation of a diagnostic composition for diagnosis and/or visualization of wounded or inflamed tissue or a disease associated therewith. Moreover, therapeutic uses are described, wherein the microorganism or cell additionally contain an expressible DNA sequence encoding a protein suitable for therapy, e.g. an enzyme causing cell death or digestion of debris.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.