Patent · US Active

Homogeneous time resolved fluorescence based test system for Paramyxoviridae

US8137921B2 · kind B2 · utility

0Cited by

0References

17Claims

0Family size

Assignee

Tibotec BVBA · BE

Inventors

Dirk André E Roymans · Turnhout, BE
Koenraad Lodewijk August Van Acker · Temse, BE
Inge Vereycken · Deurne, BE
Géry Karel Julia Dams · Beringen, BE

Key dates

Filing date	Dec 12, 2007
Grant date	Mar 20, 2012
Priority date	—
Expiry date	May 30, 2028

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/135
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention concerns a fluorescence resonance energy transfer based high throughput test system to measure the formation of the RSV F1 six-helix bundle. In a first embodiment the current invention relates to a homogeneous time resolved fluorescence-based test system comprising a first helical polypeptide consisting essentially of the sequence of IQN57 (SEQ ID NO: 1); a second helical polypeptide consisting essentially of the sequence of C45 (SEQ ID NO: 2) wherein said IQN57 is labeled with a light emitting fluorophore and said C45 is labeled with an ultra-violet excitable fluorophore.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.