Methods for producing preparations of recombinant AAV virions substantially free of empty capsids
US8137948B2 · kind B2 · utility
64Cited by
3References
8Claims
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Key dates
| Filing date | Jun 1, 2007 |
| Grant date | Mar 20, 2012 |
| Priority date | — |
| Expiry date | Jun 1, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography techniques and provide for commercially viable levels of recombinant AAV virions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.