Selected endothelial progenitor cells and methods for use
US8137968B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Feb 27, 2008 |
| Grant date | Mar 20, 2012 |
| Priority date | — |
| Expiry date | May 27, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/91
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is a method for preparing a substantially pure population of endothelial progenitor cells wherein said cells express Flk-1, CD34, α5β1 integrin fibronectin, and vWF and exhibit an adherent phenotype and methods for using the same to decrease the severity of lung injury, prevent pulmonary edema, restore endothelial barrier function, induce productive wound healing and angiogenesis, and increase survival rate in acute lung injury (ALI).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.