Biocompatible, biodegradable polymer-based, lighter than or light as water scaffolds for tissue engineering and methods for preparation and use thereof

US8137972B2 · kind B2 · utility

Assignees

• DREXEL UNIVERSITY · US
• The Wistar Institute · US
• The Trustees of the University of Pennsylvania · US

Inventors

• Cato T. Laurencin · Philadelphia, US
• Solomon R. Pollack · Dresher, US
• Elliot Levine · Cherry Hill, US
• Edward A. Botchwey, III · Decatur, US
• Helen H. Lu · New York, US
• Mohammed Khan · Philadelphia, US

Key dates

• Filing date: May 30, 2007
• Grant date: Mar 20, 2012
• Expiry date: Jul 28, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/40
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Scaffolds for tissue engineering prepared from biocompatible, biodegradable polymer-based, lighter than or light as water microcarriers and designed for cell culturing in vitro in a rotating bioreactor are provided. Methods for preparation and use of these scaffolds as tissue engineering devices are also provided.