Methods for treating a neurological disorder by peripheral administration of a trophic factor
US8138143B2 · kind B2 · utility
0Cited by
23References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 26, 2010 |
| Grant date | Mar 20, 2012 |
| Priority date | — |
| Expiry date | Aug 26, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods of treating a subject having a disease, disorder or condition of the central nervous system. The methods include administering TGF-α polypeptides, related polypeptides, fragments and mimetics thereof useful in stimulating progenitor cell or stem cell proliferation, migration and differentiation. The methods of the invention are useful to treat and prophylactically ameliorate neurological tissue injury in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.