Patent · US Active

8-oxoadenine derivatives acting as modulators of TLR7

US8138172B2 · kind B2 · utility

32Cited by
21References
14Claims
0Family size

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Key dates

Filing dateJul 3, 2007
Grant dateMar 20, 2012
Priority date
Expiry dateMar 25, 2028

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides 8-oxoadenine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The 8-oxoadenine derivatives act as modulators of Toll-like Receptor (TLR) 7 and thus may be used in the treatment of asthma, hepatitis, allergic diseases, viral and bacterial infection as well as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.