Patent · US Active

Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors

US8138353B2 · kind B2 · utility

5Cited by

24References

6Claims

0Family size

Assignee

Genzyme Corporation · US

Inventors

Bradford H. Hirth · Framingham, US
Craig Siegel · Woburn, US

Key dates

Filing date	Jul 6, 2010
Grant date	Mar 20, 2012
Priority date	—
Expiry date	Jul 6, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D498/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is a novel enantiomeric synthesis ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.