Modified beta-glucosidases with improved stability
US8143049B2 · kind B2 · utility
3Cited by
6References
21Claims
0Family size
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Key dates
| Filing date | Aug 31, 2009 |
| Grant date | Mar 27, 2012 |
| Priority date | — |
| Expiry date | Nov 5, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01021
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are modified beta-glucosidase enzymes, derived from the Trichoderma reesei Cel3A beta-glucosidase, that exhibit improved stability at low pH, low pH and high aeration, low pH and high agitation, or low pH and elevated temperature. Also provided are genetic constructs comprising nucleotide sequences encoding for modified beta-glucosidase enzymes, methods for the production of modified beta-glucosidase enzymes from host strains and the use of the modified beta-glucosidase enzymes in the hydrolysis of cellulose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.