Patent · US Active

Fusion protein of HIV regulatory/accessory proteins

US8143054B2 · kind B2 · utility

6Cited by

1References

24Claims

0Family size

Assignee

Bavarian Nordic A/S · DK

Inventors

Paul Howley · Scone, AU
Sonja Leyrer · Munich, DE
Eva Felder · Munich, DE

Key dates

Filing date	Jun 24, 2009
Grant date	Mar 27, 2012
Priority date	—
Expiry date	May 28, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2740/16334
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to fusion proteins comprising the amino acid sequence of at least three HIV proteins selected from Vif, Vpr, Vpu, Rev, and Tat or derivatives of the amino acid sequence of one or more of said proteins, wherein the fusion protein is not processed to individual HIV proteins having the natural N and C termini. The invention further concerns nucleic acids encoding said proteins, vectors comprising said nucleic acids, and methods for producing said proteins. The fusion protein, nucleic acids and vectors are usable as vaccines for the at least partial prophylaxis against HIV infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.