1-(2H)-isoquinolone derivative
US8143274B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 7, 2005 |
| Grant date | Mar 27, 2012 |
| Priority date | — |
| Expiry date | May 11, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides: a compound represented by the following formula (I):[wherein Y1 and Y4 represent a hydrogen atom or a halogen atom; either one of Y2 and Y3 represents —NR1R2, and the other represents a hydrogen atom or a halogen atom; X represents an aryl group or a heteroaryl group that may be substituted; R1 represents a hydrogen atom, or a C1-8 alkyl group that may be substituted; and R2 represents a C1-8 alkyl group that is substituted with one or more substituents, —COOR3, —COR4, —COSR5, —CONR6R7, —NR22R23, or —C═NR24R25; or R1 and R2, together with a nitrogen atom to which they are bonded, may form a 4- to 10-membered hetero ring containing at least one nitrogen atom (wherein the hetero ring may be substituted with one or more substituents selected from Group C)], a prodrug thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical, a pharmaceutical composition, or the like, which comprises the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.