Inhibitors of HCV replication

US8143288B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Michael H. Serrano-Wu · Cambridge, US
• Makonen Belema · North Haven, US
• Lawrence B. Snyder · Killingworth, US
• Nicholas A. Meanwell · East Hampton, US
• Denis R. St. Laurent · Newington, US
• Ramesh Kakarla · Doylestown, US
• Van N. Nguyen · West Haven, US
• Yuping Qiu · Princeton Junction, US
• Xuejie Yang · Longbeilingcun, CN
• John E. Leet · Madison, US
• Min Gao · 安丰镇, CN
• Donald O'Boyle · Killingworth, US
• Julie A. Lemm · Durham, US
• Fukang Yang · Madison, US

Key dates

• Filing date: Jun 5, 2006
• Grant date: Mar 27, 2012
• Expiry date: Mar 3, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having the structure of formula I are described.The compounds can inhibit hepatitis C virus (HCV) replication, and in particular can inhibit the function of the HCV NS5A protein.