Method for screening allergic disease-related molecule and cell lines to be used in the method
US8148058B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Nov 14, 2007 |
| Grant date | Apr 3, 2012 |
| Priority date | — |
| Expiry date | Sep 12, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5047
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An allergic disease-related substance is screened from candidate substances based on the reactivity to a plurality of cell lines, which are basophil-like or mast cell-like cell lines derived from the same spleen tissue and have different sensitivities to allergic cytokines. Further, an allergic disease-related substance is screened from candidate substances using at least one basophil-like or mast cell-like cell lines selected from the group consisting of R cell (Deposit No. FERM BP-10918), N 62.5 cell (Deposit No. FERM BP-10919) and RCCM cell (Deposit No. FERM BP-10920).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.