Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA

US8148345B2 · kind B2 · utility

Assignee

• Georgia Health Sciences University Rsearch Institute, Inc. · US

Inventors

• Yin Li · New Berlin, US
• Michael Farrell · Calabasas, US
• Margaret J. Kirby · Augusta, US

Key dates

• Filing date: Apr 13, 2009
• Grant date: Apr 3, 2012
• Expiry date: Apr 13, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Introduction of double stranded RNA into cells, cell culture, organs and tissues, and whole organisms, particularly vertebrates, specifically attenuates gene expression.