Patent · US Active

Substituted bicyclic pyrimidone derivatives

US8148364B2 · kind B2 · utility

0Cited by
1References
10Claims
0Family size

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Inventors

Key dates

Filing dateMay 16, 2008
Grant dateApr 3, 2012
Priority date
Expiry dateApr 3, 2030

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof:Wherein Y, Z, R1, R2, R3, R4, R5, R6, R7, n, m, and o are as described herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.