Patent · US Active

Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands

US8148429B2 · kind B2 · utility

4Cited by

25References

12Claims

0Family size

Assignee

ANAMAR AB · SE

Inventors

Torbjorn Lundstedt · Bjärred, SE
Anna Skottner · Ekerö, SE
Elisabeth Seifert · Uppsala, SE

Key dates

Filing date	Dec 15, 2006
Grant date	Apr 3, 2012
Priority date	—
Expiry date	Oct 28, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D317/58
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the use of compounds of general formula (I) as ligands to the melanocortin receptors and/or for treatment of disorders in the melanocortin system: wherein X is H or OH; R1, R2, R3, R4 and R5 are the same or different and are selected from hydrogen, halogen, alkyl having 1 to 5 carbon atoms, electron donor groups such as alkoxy having 1-5 carbon atoms or hydroxy, electron acceptor groups selected from cyano, nitro, trifluoroalkyl or amide; alkylamino, benzoyloxy, nitroxy, phenyl or sulpho; and the pharmacologically active salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.